Abstract
A deficiency in lipids and ceramides is an indicator of a compromised skin barrier. Previous research has shown that skin can create new longer chain fatty acids and ceramides from topically applied fatty acid containing moisturizers, if successfully delivered, to help replenish the skin’s barrier. It has also been previously shown that topically applied ceramides do not penetrate as effectively as fatty acids and are therefore not as efficient at replenishing the skin barrier. The objective of this research was to determine if moisturizers with fatty acids can more effectively repair barrier-disrupted skin than ceramide-containing moisturizers in an ex vivo model.
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