Abstract
Our aim was to compare the efficacy and safety of IMN with concurrent use of oxytocin versus EASI for cervical ripening and labor induction. One hundred nulliparous pregnant women of at least 41 week’s gestation, with Bishop score <5 were selected, blind randomely to receive vaginally either 60 mg IMN or EASI procedure. Forty-eight percent who treated with IMN went to active phase of labor compared to thirty-one in EASI Group(P<0.01). Mean interval time to active phase was shorter in IMN group (3 hours versus 4.6 hours, P<0.01). We were unable to demonstrate a statistically significant difference between two groups in incidence of cesarean and vaginal delivery (p=0.37). Headache was the common side effect with moderate intensity in IMN group. Outpatient cervical ripening &labor induction with IMN seems to be an effective, safe and well tolerated procedure. No difference in intrapartum complication, neonatal outcome or maternal morbidity were found. IMN/Oxytocin result in a shorter induction to vaginal delivery time compare with EASI.
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