Abstract
In recent years, NIRS has been widely utilized for monitoring oxygen metabolism of human brain. Though NIRS can measure two kinds of hemoglobin, only oxy-Hb has received attention as a criterion for judgment of a brain function. Therefore, implications of changes in deoxy-Hb have not been revealed enough and have to be investigated from a physical viewpoint. In this study, numerical simulation of oxygen transport to cerebral tissue is conducted to obtain transient hemoglobin changes with different blood flow rate to short stimulations. Our numerical results suggest that increase in deoxy-Hb during stimuli shows physiological signals coming from capillaries.
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