Abstract
Five commercial kits including Staclot PNP, Staclot LA, PTT-LA, and 2 dilute Russell's viper venom time tests for detecting lupus anticoagulant were determined in 102 patients with systemic lupus erythematosus (SLE). The 5 coagulation tests had different positive rates ranging from about 4 to 9%, and the patients might have different result by using different test. If we regarded a patient with two or more positive LA tests as being positive, 8% of the SLE patients in our study were LA positive. Among the 5 LA tests, the highest correlation was between DVVtest and LA-Screen & LA-Confirm (k=0.648), and the test having the highest correlation with the remaining other 4 tests was Staclot LA (k=0.864). The consistency of LA tests and anti-cardiolipin antibody test was good. Due to the heterogeneity of the results of LA tests, the diagnosis of the presence of LA in a patient should be carefully made if only one LA-positive test was obtained.
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