332P A phase II, open-label, single-center study of QL1706 plus platinum doublet chemotherapy with bevacizumab as first-line treatment in patients with advanced NSCLC: Data from EGFR mutant cohort

Abstract

QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, showed promising antitumor efficacy in advanced solid tumors including NSCLC in a phase (Ph) I trial. Here, we report the efficacy and safety results from the EGFR mutant cohort of an ongoing Ph II study of QL1706+chemotherapy (chemo)+bevacizumab in patients (pts) with advanced NSCLC.