Abstract

s S129 Results: Figure shows representative waveforms of pump speed, AoP, and pump flow with sinusoidal pump speed modulations of 0%, ±15% and ±25%. The AoP pulse pressure significantly increased to 12.7 mm Hg and 17.7 mmHg with ±15% and ±25% speed modulations, respectively (Table). There were no changes in the mean AoP, mean pump flow, or left atrial pressure. Conclusion: The feasibility to generate pressure pulsatility by pump speed modulation with the CFTAH was validated. This unique platform is suitable for evaluating the physiologic impact of pulsatility and allows determination of the best speed modulations in term of magnitude, frequency, and profiles.

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