32661 Clinical evaluation of deodorant efficacy and tolerance for overall body odor control

Abstract

Sweating and associated odor negatively impact self-confidence and social acceptance as they are linked to poor hygiene. Rapid multiplication of bacteria and sweat breakdown causes malodor. High “sweaters” e.g. with hyperhidrosis, are more susceptible to developing body odor. While deodorants for the axilla are used to contain odor, there is need for products to help eliminate other body part odors as well. A randomized, blinded clinical study in healthy volunteers (F, 18-67y) testing involving 3 body odor control products with completion of 90 volunteers (30 per arm). Clinical design involved 1 randomized underarm designated as the treatment site, receiving 1 of 3 test products with the other underarm remaining untreated. Four expert graders conducted underarm visual and malodor assessments at 8, 12, 24, 48, and 72 hrs after final product application. Efficacy of the product on vaginal/perineal/anal malodor was determined at 8 hours after application. The results of the comparative malodor analysis indicated significant differences between products at all assessment intervals favouring PCR Code A as statistically more effective in controlling malodor at all timepoints. Posttreatment malodor scores with PCR Code A use on their private parts indicated a significant reduction in malodor from baseline, 8 hours postapplication. Subject perception showed highly favourable results for product attributes of feel, texture, no residue, odor reduction, skin tolerance, and dual purpose. In conclusion, the dual-purpose deodorant with its clinically proven performance in terms of feel, odor control and low skin irritation potential is effective in controlling arm pit and vaginal/perineal/anal odor.