Abstract
η6-(Arene)chromium complexes have seen considerable development for organic synthesis on the basis of the strong electron-withdrawing ability and steric effects of the tricarbonylchromium fragment. The corresponding arene chromium complexes of unsymmetrical 1,2- or 1,3-disubstituted arene ligands are no longer superimposable on their mirror images. Enantiomerically enriched planar chiral arene chromium complexes are accessible by both resolution and asymmetric synthesis. The latter method includes diastereoselective complexation, diastereoselective or enantioselective lithiation/electrophilic quenching, and nucleophilic addition/hydride abstraction. Catalytic asymmetric synthesis of planar chiral arene chromium complexes with chiral catalysts is also described. Planar chiral tricarbonyl(arene)chromium complexes have been widely used in asymmetric synthesis and natural product synthesis, and increasingly as chiral ligands in asymmetric catalysis. This chapter focuses on the synthesis of planar chiral arene chromium complexes and their preparative applications for organic synthesis. Additionally, the synthesis of Fischer-type carbene chromium complexes is briefly described.
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