#3253 STUDY OF THE EFFECT OF TWO BARIATRIC SURGERY TYPES ON RENAL FUNCTION AND MCP 1 LEVELS

Abstract

Abstract Background and Aims Bariatric surgery has been the most effective and permanent treatment for severe obesity and has resulted in significant improvement or reduction of comorbidities due to obesity. To evaluate and compare the outcome of two types of bariatric surgery (LMGB and LSG) on renal functions and urinary MPC-1 level in morbidly obese patients after three months of surgery. Method Forty morbidly obese patients underwent bariatric surgery between October 2018 and July 2019. Two types of bariatric surgery were done; laparoscopic mini gastric bypass (LMGB) and laparoscopic sleeve gastrectomy (LSG). Group A include 26 patients underwent LSG and group B include 14 patients. Results There were no statistically significant difference in the postoperative mean weight, BMI, neck circumference, WC, Hip circumference, WHR, SBP and DBP in the cases between the 2 types of surgeries (LSG and LMGB) also, there were no statistically significant difference in the mean post urinary MCP1 (73.53±21.25&75.43±26.17,P>0.5), post microalbuminuria (8.83± 6.26 &10.02± 8.6,P>0.05),post urinary creatinine (109.21± 43.22&99.19±48.65,P>0.05), post MCP1/Cr ratio (0.78±0.36&1.01±0.70,P>0.05), post CRP(5.73± 3.04&5.77±3.17, P>0.05), post serum creatinine (0.74±0.05&0.75± 0.07,P>0.05), eGFR (100.32±9.54&104.39±9.54,P>0.05), s.cholesterol, s.HDL and s.TGs in the cases who had either LSG operation (group A) or LMGB operation (group B). Conclusion There were no statistically significant difference as regard renal function, urinary MCP-1 level and weight loss between LSG and LMGB.