324: Women in the intensive unit care of cardiology: morbidity and mortality study

Abstract

The aim of this observational study that includes 800 consecutive patients admitted in our unit intensive care of cardiology (UIC) is the evaluation of the cardiac pathology in women, and the morbidity and mortality of them compared to men. The women represent 25% of patients, they were older (mean age 66 ±5 years versus 56±7 years in men, p=0.05), and we observed more diabetes 48.6% vs 38%, p=0.003. The diagnostic of acute coronary syndrome without ST elevation were relieved in 43% of women vs 24% in men, p=0.03. STEMI were more frequent in men (24% vs 32%), the auriculo ventricular block were more frequent in women 16.8% vs 5%, p=0.002. We observed in women patient a higher incidence of cardiac arrest resuscitated (2.5% vs 1.7% p=0.05) and cardiac shock 3.2% vs 0.7%, p=0.004. Insides a better left ventricular ejection fraction (47±15% vs 40±14%, p=0.03), they presented more hemodynamic complication (6% versus 2.8% in men, p<0.01) and more rhythmic complication (8% versus 4.5% in men, p<0.01) Angiographic Coronarography were performed in 61% of women compared to 77% in men. A coronary revascularization by percutaneous transluminal coronary angioplasty were performed in 9% of women vs 11.5% in men, and only 9.6% of women beneficed of chirurgical revascularization versus 14.3% of men, p=0.004 Finaly, we observed more mortality in our study in women patients (3.2% vs 1.8%, p=0.002). The predictive factors of mortality were the level of the CRP (odds ratios and 95 percent confidence intervals =7.6, 1.1–14.3, p=0.013) and the female gender (OR at 3.8, CI at 95% a =1.2–5.4, p=0.0013) and the LVEF (OR at 1.4, CI aT 95% =1.1–7.8, p=0.012), but only the female gender was in independent predictive factor of mortality in IUC of cardiology using multiple logistic regression to estimate the adjusted odds raio (OR adjusted a 1.7, CI at 95% =1.11–5.4, P= 0.002). The women presented only the quart of the patients admitted in the intensive unit care of cardiology, but this population have a higher level of morbidity, hospital complication. More, the female gender in an independent predictive factor of mortality.