Abstract
The rise in the use of opioids has been accompanied by escalating rates of prescription opioid misuse and addiction in patients with pain. Research has shown that opioid craving is a robust determinant of prescription opioid misuse. There is reason to believe that hedonic feelings associated with opioid use (e.g., pleasure, satisfaction) could also contribute to opioid misuse. However, this has yet to be examined in patients with pain. In this longitudinal study, the first objective was to examine the association between opioid-related hedonic feelings and prescription opioid misuse in patients with chronic pain. We also examined the factors contributing to opioid craving and opioid-related hedonic feelings in these patients. The method and design constituted of 14-day longitudinal diary study, patients (n=38) completed daily diaries assessing pain, psychological, and opioid-related variables. Prescription opioid misuse was also assessed. A multilevel analyses revealed that daily levels of pain intensity, negative affect, and catastrophizing were significantly associated with opioid craving (all p's
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