3212: Endosonographic follow-up in patients with early chronic pancreatitis: Case studies

Abstract

Objectives: Although, in Western country, there were many studies that the usefulness of endosonography (EUS) for diagnosis of CP, it is thought that the EUS-diagnosis of CP is ambiguous since EUS findings sometimes depend on the each endoscopist. To investigate whether EUS-criteria of CP diagnosis is propriety or not, we examined the changes of the CP-EUS findings in patient with early CP diagnosed by EUS. Methods: Seven patients with unexplained mid-epigastric and/or periumbilical abdominal pain who was suspected early CP in EUS criteria were studied. They underwent more than twice EUS-examination. EUS criteria was used as follows. A: Parenchymal features; 1. hyperechoic foci, 2. hyperechoic strands, 3. lobular out gland margin, 4. lobularity, 5. inhomogenous echo. B: Ductal features; 1. hyperechoic ductal margin, 2. duct dilation, 3. duct irregularity, 4. side-branches dilation. All patients had administrated Camostat mesilate after fist EUS. Results: Mean follow-up period was 18.7 mo. In two cases, the number of EUS-criterion was diminished. In five cases, no change of the number of EUS-criterion was noted. Conclusions: In study patients, the EUS-findings were constitutively identified in each examination during EUS follow-up. Thus, EUS-criteria will be feasible in the diagnosis of CP.