32 Automatization of clinical VMAT plan verification with PRIMO

Abstract

Introduction With version 0.3.1, PRIMO allow to easily calculate dose for VMAT clinical plans with Monte Carlo. Recent enhancements in latest beta version open the way to a seamless plan calculation workflow with PRIMO. Methods We used 2 functionalities recently added to PRIMO in latest beta versions. The first one is the macro mode. It allows to run from a very simple command files all actions needed to start a VMAT plan calculation (CT, plan, structure and dose import, phase space setting, simulation parameters setting, and even perform gamma analysis). These are the same than actions performed usually through graphic interface. The second one is the ability to create/open a PRIMO project (and run a macro command file) from command line. We implemented a Python script to watch a directory content. As soon as a set of DICOM files is created, the script launches PRIMO for a new project, specifying a predefined macro file (and automatically adapted to the plan to simulate). The phase space is set regarding linac and energy. Results We developed a prototype able to calculate a VMAT plan by Monte Carlo with PRIMO in a fully automated way, based on latest features in PRIMO. The only required action is to export DICOM files (CT, plan, structures and dose) from TPS to have the plan calculated by PRIMO, including gamma analysis integrated to PRIMO. Current developments will lead to a queuing system combined with a dashboard that will show (with a web page) an overview of simulated plans. The aim is to integrate these features in PRIMO. Conclusions Latest PRIMO features open the way to a fully automatized VMAT plan verification with PRIMO, with a minimal configuration effort.