Abstract
G A A b st ra ct s the waaWVL operon is not present in non pathogenic E. coli strains but is present in most AIEC from our collection and in two other sequenced AIEC strains NRG 857C and UM146. CONCLUSION: The presence of waaWVL operon is essential for AIEC bacteria to form biofilm at the surface of the intestinal mucosa. The search for the presence of the waaWVL operon could represent a useful molecular tool to identify pathogenic AIEC and targeting waaWVL operon expression could be a very potent therapeutic strategy to interfere with the ability of AIEC to form biofilm on the gut mucosa of Crohn's disease patients.
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