31. The PT alphabet soup: LDT, FDA, NGS, non-NGS, @#$!%

Abstract

The performance of laboratory testing has recently come under increased scrutiny as part of important and ongoing debates on regulation and reimbursement of laboratory developed tests (LDTs), including next generation sequencing (NGS). The College of American Pathologists (CAP) is a well- recognized provider of external proficiency testing (PT) materials that provide a mechanism for laboratories to fulfill Clinical Laboratory Improvement Amendments. The CAP Molecular Oncology Committee has examined the overall performance of laboratories across specific single analytes as well as NGS PT surveys.