3.0T intraoperative application of magnetic resonance in glioma resection

Abstract

Objective To investigate the 3.0T high-field intraoperative MR imaging applications in surgical resection of gliomas. Methods One hundred and fifty-two patients with brain gliomas, admitted to our hospital from January 2011 to December 2013, were enrolled in our study; tumor resection was performed in 85 patients under the guidance of a simple neural navigation (control group) and 67 patients under intra-operative MRI neuronavigation (iMRI group). A retrospective analysis was performed on the clinical data of the patients; tumor resection rate, surgical time and prognosis of the patients were analyzed and compared between the two groups. Results All the 152 patients were successfully performed tumor resection. Longer surgical time was needed in patients of iMRI group than that in the control group, with significant difference (P<0.05). In the iMRI group, total resection was achieved in 60 patients, subtotal resection in 4, greatly partial resection in two, and partial resection in one; in the control group, total resection was achieved in 61 patients, subtotal resection in 8, greatly partial resection in 9, and partial resection in 7; the resection rate in the iMRI group was significantly higher than that in the control group (P<0.05). The good prognosis rate in the iMRI group (94.0%) was significantly higher than that in the control group (72.9%,P<0.05). No MRI-related adverse events or infected patients were noted. Conclusion 3.0T high-field intraoperative MRI technology helps intra-operative brain shift in real-time to correct the error, pinpoint glioma imaging edge to maximize clinical glioma resection, retain neurological areas and improve prognosis of the patients. Key words: Intra-operative MR imaging; Neuronavigation; Glioma; Resection rate; Prognosis