Abstract
This study aims to understand the relationship between the genetic polymorphisms of IL-1β, COX2 and EP4 and the biochemical parameters of the complete blood count in patients with psoriasis. 63 psoriasis patients were analysed and divided based on PASI: <5 (G1) and ≥5 (G2). Determination of IL-1β (rs16944; A>G), COX-2 (rs20417; G>C) and EP4 (rs4613763; T>C) was performed by endpoint genotyping. A statistically significant value of p<0.05 was considered. Allele A of IL-1β polymorphisms showed a 4.23-fold risk [1.22-14.59] for G2.
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