308 Poster - Characterization of 331G/A polymorphism of rp gene and identification of viral oncogene HMTV virus as genetic markers for the improvement of breast cancer management in Cameroon

Abstract

Background: Breast cancer is a real public health problem in Cameroon, where more patients with this cancer usually die a year after diagnosis, as it is still based on histological examination, mortality due to cancer is far from decreasing. Since cancer is an accumulation of molecular changes, the +331 G/A polymorphism of PgR gene (progesterone receptor) and viral oncogene HMTV (Human Mammary Tumor Virus) has been recently considered as a molecular markers associated with breast cancer. Due to that, we fixed our objectives to characterize these markers by semi-nested PCR to understand etiological factor of that cancer in Cameroon.