3074: Ultrasound characteristics of ductal carcinoma in situ of breast with negative mammogram

Abstract

Objectives: To demonstrate ultrasound features of mammographically undetected ductal carcinoma in situ of breast and to evaluate the value of ultrasound in examining that condition. Methods: Thirty-seven cases were found to have ductal carcinoma in situ out of 685 cases performed by core needle biopsy. The study comprised of eight of them, whose mammograms taken before and after ultrasound had been proved negative by two radiologists. Clinical symptoms, parenchymal pattern on mammogram were classified. Ultrasound features of detected lesions were described according to the BI-RADS lexicon and pathologic type was classified. Results: Clinically occult cases were three, and palpable mass and bloody nipple discharge were manifested in three and two, respectively. All mammograms showed heterogeneously or extremely dense parenchyma. The mean lesion diameter was 16 mm (range, 1 to 65 mm). Their ultrasound features were nonspecific but generally showed hypoechoic masses with or without ductal extension. Some of them were similar to that of benign breast lesions, but all lesions except one had been classified BI-RADS category 4 or 5. All ductal carcinoma in situ lesions proved to be noncomedocarcinoma (two cribriform, three micropapillary, two papillary, one solid). Conclusions: Ultrasound can be useful in detecting and characterizing mammographically undetected ductal carcinoma in situ of breast.