Abstract
Previous theories considered that the main cause of motor cortex stimulation (MCS)-induced antinociception was due to opioid participation in periaqueductal gray (PAG). However, recent evidence indicated that melanocortinergic signaling in PAG plays an important role in neuropathic pain. A number of studies verified that the neurotropic pseudorabies virus (PRV) provided a highly specific method of mapping the motor and sympathetic pathways innervating a variety of targets. The goal of the present study was to elucidate whether the sympathetic neuronal circuitry existed among MC, PAG and spinal cord by PRV-614 injection to the left gastrocnemius muscle in MC4R-GFP transgenic mouse.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
