Abstract

• The current randomised, Phase III study (LUME-Lung 1; NCT00805194) was designed to investigate the efficacy and safety of nintedanib 200 mg twice daily (bid) in combination with docetaxel versus placebo and docetaxel for the treatment of patients with advanced or recurrent NSCLC who had previously failed first-line chemotherapy – during this study, patient-reported quality of life (QoL) was recorded at regular intervals using standard QoL questionnaires and so the effect of treatment on prespecified symptoms of interest in patients with NSCLC is also examined RESULTS

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