Abstract
We report a one-pot metal-free synthesis of 3-nitro-coumarins from aryl alkynoates using TBN (tert-butyl nitrite) as the sole reagent. The radical triggered cyclization and nitration of the aryl alkynoates proceeded in a cascaded manner via nitro radical addition to alkynoates, then 5-exo-trig spirocyclization and ester migration.
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