Abstract
Uterine leiomyomas are benign tumors regulated by gonadal hormones and are composed of an abundance of disorganized extracellular matrix (ECM). Unfortunately, improved understanding has been hampered by limited, technically-difficult, or unreliable in vivo model systems. The goal of this study was to establish a reusable, well maintained source of transplanted material to validate a mouse xenograft model for the study of uterine leiomyomas.
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