Abstract
Researchers have found a way to print complex 3-D structures inside live mice (Nat. Biomed. Eng. 2020, DOI: 10.1038/s41551-020-0568-z). By injecting a light-sensitive bioink and then shooting infrared pulses at it from outside the body, they made scaffolds in the brain, skin, and muscle that could be loaded with stem cells to aid tissue regeneration. This could lead to a noninvasive technique to repair injured or diseased tissues and organs inside the body without requiring surgery. In recent years, scientists have used 3-D bioprinting to make implantable skin, blood vessels, and heart and liver tissues. They can also print porous scaffolds that are loaded with stem cells and implanted in the body, where they form new tissue. These printed tissues could help regenerate damaged skin and cartilage or patch diseased heart and lung tissue, but they must be surgically implanted. “There’s no way to escape from surgery so far,” says
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