Abstract
In the title compound, C17H20Cl2N4O, the piperazine ring adopts a chair conformation and the dihedral angle between the pyridazine ring and the benzene ring is 36.3 (1)°. In the crystal, weak C—H⋯O and C—H⋯(N,N) interactions help to establish the packing, which also features short intermolecular Cl⋯Cl contacts [3.331 (2) Å].
Highlights
In the title compound, C17H20Cl2N4O, the piperazine ring adopts a chair conformation and the dihedral angle between the pyridazine ring and the benzene ring is 36.3 (1)
Pyridazine derivatives are important aromatic heterocycle compounds in the field of medicinal chemistry: for example, 3-(piperazin-1-yl)pyridazine derivatives are reported to possess anti-inotropic, anti-blood platelet aggregation (Monge et al, 1991), anti-bacterial (Tucker et al, 1998) and anti-viral activities (Fan et al, 2009)
The mixture was stirred for 24 h at room temperature (Shi-Yong Fan et al, 2009)
Summary
Refinement a School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China, and bBeijing Institute of Pharmacology and Toxicology, Beijing 100850, People’s Republic of China. R factor = 0.050; wR factor = 0.159; data-to-parameter ratio = 13.8. C17H20Cl2N4O, the piperazine ring adopts a chair conformation and the dihedral angle between the pyridazine ring and the benzene ring is 36.3 (1). Weak C—H O and C—H (N,N) interactions help to establish the packing, which features short intermolecular Cl Cl contacts [3.331 (2) Å]
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