3-ALKYL-2-PHENYL-1-VINYLPYRROLES FROM KETOXIMES AND ACETYLENE: AN IMPROVED SYNTHESIS BY THE TROFIMOV REACTION

Abstract

A one-pot synthesis of 3-alkyl-2-phenyl-1-vinylpyrroles, giving high yields at atmospheric pressure, was developed on the basis of reacting alkyl phenyl ketoximes with acetylene in a KOH–DMSO system (the Trofimov reaction). Authors: O. V. Petrova, L. N. Sobenina, and A. I. Mikhaleva English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (11), pp 1628-1633 http://link.springer.com/article/10.1007/s10593-013-1184-6