Abstract
Oxadiazoles are 5-membered, unsaturated, unstable, heteroaromatic ring containing two carbon atom, one oxygen atom and two pyridine type nitrogen atom linked in continuity. They fall under non beta lactam class of antibiotics. Oxadiazoles are potent inhibitors of mycolic acid synthesis. Mycolic acids are long fatty acids important for cell wall formation in class of bacterias called Mycolata taxon. The article focuses on various scaffolds of 1, 2, and 4- oxadiazole having inhibitory action on mycolic acid synthesis and can be applied for anti-tuberculosis treatment.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have