Abstract
3:4-Benzpyrene as an -SH Inhibitor
Highlights
Calcutt and Newhouse (1948) found that the photodynamic action of benzpyrene was inhibited by cysteine hydrochloride
The expenses of this research were defrayed out of a block grant from the British Empire Cancer Campaign
Samples from each were tested at intervals with nitroprusside. In this way it was found that inhibition of the -SH of cysteine hydrochloride, thiomalic acid, thioglycollic acid and 2-mercaptoethanol occurred in the tubes containing benzpyrene
Summary
Calcutt and Newhouse (1948) found that the photodynamic action of benzpyrene was inhibited by cysteine hydrochloride. Further work (Calcutt, 1948) showed that certain other -SH-containing compounds were effective as inhibitors of photodynamic action. In this way it was found that inhibition of the -SH of cysteine hydrochloride, thiomalic acid, thioglycollic acid and 2-mercaptoethanol occurred in the tubes containing benzpyrene.
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