Abstract
Cariprazine is a dopamine D3/D2 and serotonin 5-HT1A receptor partial agonist. This study evaluated the safety, tolerability, pharmacokinetics (PK), and exploratory efficacy of cariprazine and its 2 major active metabolites, desmethyl cariprazine (DCAR) and didesmethyl cariprazine (DDCAR) in pediatric patients with ASD.
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