Abstract
N1, N4- Bis(3-(dimethylamino)propyl)succinamide (DAPS) has been synthesized and utilized to+produ3,3′-[succinylbis(diazaneyl)]bis(N,N,N-trimethylpropan-1-ammonium) perchlorate (SAPAP). Both DAPS and SAPAP were characterized using different spectroscopic techniques. Structure of the SAPAP has been determined using single crystal X-ray diffraction technique. The compound SAPAP had excellent anticancer activity against the human colon carcinoma cell line (HT-29), proposing them as a suitable candidate for future anticancer therapies. Docking, Molecular dynamics simulation, pharmacokinetic predictions and ELISA were also employed to evaluate the inhibitory action of the synthesized compound against the said cancer cell line HT-29.
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