3.3 CLINICAL GENETIC TESTING, PRECISION MEDICINE, PATIENT REGISTRY ENROLLMENT, AND RISK-BASED COUNSELING IN AUTISM SPECTRUM DISORDER

Abstract

Molecular genetic studies of the effects of rare, pathogenic mutations have provided deep insights into mechanisms of causation for all forms of autism spectrum disorder (ASD) and highlight a new opportunity to specify treatment, prognosis, family recurrence risk, and the prospective management of common “comorbidities” that exacerbate the severity of impairment in ASD.