2-year follow-up study in patients with acute myocardial infarction

Abstract

Objective To investigate the in-hospital, 1-year and 2-year mortalities in patients with acute myocardial infarction (AMI) and the associated risk factors. Methods The 424 AMI patients were selected finally during 2007 to 2010 in our hospital. In-hospital, 1-year and 2-year mortalities were obtained by means of case inquiry, phone call and Hospital Information System (HIS). Results The in-hospital, 1-year and 2-year mortalities were 4.2%, 14.4% and 17.5%, respectively. The management of AMI patients became more standardized on the basis of guidelines. Logistic regression analysis showed that heart failure history and left ventricular ejection fraction (LVEF) was related to in-hospital, 1-year and 2-year mortalities of AMI. The OR(95% CI) of heart failure history were 7.66(2.35-25.00), 5.94(3.32-15.21) and 4.83(1.94-12.01), respectively. The OR(95% CI) of LVEF were 0.93(0.88-0.98), 0.97(0.23-0.99) and 0.96(0.94-0.98), respectively. Age was related to 1-year and 2-year mortalities. The OR(95% CI) were 1.15(1.10-1.22) and 1.14(1.10-1.20). In regard to concomitant diseases, respiratory failure and gastrointestinal bleeding were related to in-hospital mortality of AMI, and the OR(95% CI) were 5.11(1.28-20.45) and 6.83(1.65-28.22). Stroke, pneumonia, respiratory failure, gastrointestinal bleeding and tumor were related to 1-year mortality of AMI, with the OR(95% CI) were 4.35(1.30-14.53), 6.92(2.69-17.80), 4.17(1.45-14.99), 4.74(1.37-16.41) and 6.14(1.52-24.79), respectively. Pneumonia, respiratory failure, gastrointestinal bleeding, tumor and renal dysfunction were related to 2-year mortality of AMI, with the OR(95% CI) were 4.39(1.71-11.11), 4.22(1.48-12.06), 4.93(1.39-17.45), 10.62(2.72-41.54) and 1.63(1.03-2.56), respectively. Conclusions Heart failure history and age may be the independent risk factors of in-hospital, 1-year and 2-year mortalities of AMI. Pneumonia, respiratory failure, gastrointestinal bleeding, tumor and renal dysfunction may be associated with increased risk of in-hospital, 1-year and 2-year mortalities in AMI patients. Key words: Acute myocardial infarction; Mortality; Risk factors; Concomitant diseases