Abstract

In the title compound, C37H32N2O3, an intra­molecular O—H⋯N hydrogen bond generates a five-membered ring, producing an S(5) motif. The piperidone ring adopts a half-chair conformation. The two fused pyrrolidine rings have similar envelope conformations. The interplanar angles between the benzene rings A/B and C/D are 75.68 (7) and 30.22 (6)°, respectively. In the crystal structure, adjacent mol­ecules are inter­connected into chains propagating along the [010] direction via inter­molecular C—H⋯O hydrogen bonds. Further stabilization is provided by weak C—H⋯π inter­actions.

Highlights

  • H N hydrogen bond generates a five-membered ring, producing an S(5) motif

  • The interplanar angles between the benzene rings A/B and C/D are 75.68 (7) and

  • Adjacent molecules are interconnected into chains propagating along the [010] direction via intermolecular C—H O hydrogen bonds

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Summary

Structure Reports

2-Hydroxy-16-[(E)-4-methylbenzylidene]-13-(4-methylphenyl)-12-phenyl1,11-diazapentacyclo[12.3.1.02,10.03,8.010,14]octadeca-3(8),4,6-triene-9,15dione School of Chemical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia, bSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia, and cX-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia R factor = 0.047; wR factor = 0.139; data-to-parameter ratio = 20.4.

Bruker APEXII DUO CCD areadetector diffractometer
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The synthetic chemistry work was funded by Universiti
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