Abstract

Mucoepidermoid carcinoma (MEC) of the breast is an extremely rare form of salivary gland-type tumor morphologically characterized by four types of cells (basaloid, intermediate, epidermoid, and mucinous) arranged in solid and cystic patterns. Despite its triple-negative phenotype, breast MECs are reported to have a relatively good clinical behavior. However, no data on their biology and therefore no guidelines for their clinical management are currently available. Here, we sought to characterize the molecular landscape of breast MECs.

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