299 Interest of systematic screening of metabolic syndrome and high cardiovascular risk in French general healthy population

Abstract

Cardiovascular disease is a leading cause of death in France; knowledge of the importance of risk factors is an important issue. Between May 2006 and December 2008, in coordination with the regional health insurance fund of the Hauts-de-Seine area (CPAM 92), we performed a systematic screening of cardiovascular risk factors and metabolic syndrome in a population of men from 45 to 60 years old and women between 55 and 70 years old without any cardiovascular medical history. 50 000 questionnaires have been sent to residents of nine cities in Hauts-de-seine area. Answering selection questionnaires rate is about 22% (10764 persons). 8038 participants were enrolled in our study. 4 081 men (54 years old middle-age) and 4 227 women (62 years old middle-age) have been included. Among this population, 2000 (20%) persons have a medical history of hypertension (not well balanced for 51% of them), 1716 have an unknown hypertension. 20% of participants has a known dyslipidemia (not well balanced: 16%) and 1679 an unknown dyslipidemia (22%). 685 (8,5%) persons have a medical history of diabetes (not well balanced for 52% of them) and 218 an unknown one. Smokers represents 21% oh this population, more frequently men (28%) than women (13%). Abdominal obesity prevalence is very high representing in our study 3 100 persons (38%) and affects women (51%) more often than men (24%). Metabolic syndrome concerns 15% of the patients (17% of men, 13% of women). Sleepiness on the Epworth sleepiness scale represents 9%. After global cardiovascular risk assessment, 732 (9%) persons were classified at high risk of cardiovascular events, 2600 (33%) persons at moderate risk and 4700 (58%) at lower risk. According to the important prevalence of patients with a high risk of cardiovascular events, our study demonstrates the interest of a systematic primary screening in a French healthy population.