296-POS

Abstract

Objectives To assess the Doppler data finding in predicting adverse pregnancy outcomes like developed pre-eclampsia and fetal growth restriction (FGR). Methods Doppler study was done on 1222 high risk patients. These patients were followed and abnormal pregnancy outcomes were noted. Uterine artery flow velocity forms were studied. Results Resistance Index as a single parameter is the best indicator with highest sensitivity and negative predictive value. However, combination of parameters is the best indicator. There was a high incidence of developed pre-eclampsia and FGR when there were abnormalities in uterine artery indices, sensitivity ranging from 30% to 90% while specificity from 63% to 90%. When multiple indices were abnormal, 55–63% of patients developed pre-eclampsia and FGR. When both normal only 2.4% patients developed hypertensive disorders of pregnancy and 2.1% patients developed FGR. Conclusions The combination of uterine artery indices is the best indicator for prediction of hypertensive disorders of pregnancy and FGR. Bilateral diastolic notch in the uterine artery as a single parameter is more specific than the individual Doppler indices in uterine artery. Women with normal Doppler flow in uterine artery constitute a group of low risk of developing obstetric complications compare to abnormal flows. Uterine artery Doppler may be included in hospitals to identify a group of patients at risk of developing hypertensive disorders of pregnancy and poor fetal outcome. Disclosures S. Agrawal: None. T. Nagar: None. S. Khoiwal: None. S. Arora: None. S. Agrawal: None. K. Jayant: None.