296 Histologic Pattern of Abnormal Uterine Bleeding in Endometrial Curetting in Lagos University Teaching Hospital in 2015

Abstract

Abnormal uterine bleeding (AUB) is a common presenting complains in the gynecological out-patient department. Histopathologic evaluation of endometrial curettings plays an important role in diagnosing these cases. The aim of this study is to determine the histopathologic spectrum of endometrial curettings in women with AUB submitted to the Department of Anatomic and Molecular Pathology at Lagos University Teaching Hospital from January to December 2015. Histopathology reports of women with AUB were retrieved from the departmental archives. The diagnoses were categorized and analyzed. Fifty-four curettings performed for AUB were seen during the study period. The age range was 22 to 77 years. Most cases (63%) were seen in the perimenopausal period (40s to 50s). Non-atypical hyperplasias accounted for the majority (33.3%), followed by endometrial polyps (24.1%), endometrial malignancies (22.2%), stromoglandular differentiation (5.6%), and normal endometrium (5.6%). Endometritis was seen most commonly in the 30s, while malignant neoplasms peaked in the 60s. Normal endometrium, endometrial hyperplasias, polyps, and stromoglandular dissociation were seen most commonly in the perimenopausal period. Histopathologic examination of endometrial curettings reveals a wide spectrum of changes, especially in the perimenopausal period. Histologic examination is especially warranted in this age group.