293-POS

Abstract

Objectives For decades, preeclampsia has been known to be a disease related with placenta ischemia. Many studies have been done to look for the evidence of biomarkers in blood and/or umbilical artery waveforms by vascular Doppler ultrasound that could predict placental ischemia. In this study, we explored if umbilical artery velocity would be a better indicator of the ischemia of the fetal-placenta circulation. Methods 65 early-onset preeclampsia cases were included. We recorded their umbilical velocity and waveforms using Doppler ultrasound when they showed any abnormal clinical symptoms such as hypertension, urine protein or FGR. The criteria for abnormal umbilical artery velocity was systolic velocity 3, RI > 0.7, PI > 1.1. Results 56 of 65 cases showed abnormal umbilical artery velocity (86.15%). In contrast, only 28 of 65 cases showed abnormal umbilical artery waveforms (43.08%), P Conclusions The umbilical artery velocity is more sensitive than the umbilical artery waveform in predicting ischemia of the fetal-placental circulation. Disclosures Y. Shen: None.