Abstract
We numerically investigate migration of biological polymers through a microchannel with periodically spaced electrodes. The numerical model is based on Brownian dynamics simulation of bead-spring chain. Electric potential inside the channel is determined by solving the linearized Poisson-Boltzrnann equation using the boundary element method. In this study, we mainly discuss mobility of biological polymers which would depend on the chain length of the model and on voltage of the electrodes. The present numerical technique would provide useful suggestions for future researches and basic design tools for practical μ-TAS devises.
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