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Abstract

Introduction: Centrifugal blood pumps are being increasingly utilized in children supported with extracorporeal membrane oxygenation (ECMO). Hypothesis: Our aim was to determine if survival and ECMO related morbidities in children supported with veno-arterial (VA) ECMO differed by blood pump type. Methods: Children < 18 years old who underwent veno-arterial ECMO support from 2007 – 2009 and reported to the Extracorporeal Life Support Organization registry were propensity score matched (Greedy 1:1 matching) using pre-ECMO characteristics. Results: A total of 2656 (centrifugal=2231, roller=425) were identified and 548 patients (274 per pump type) were included in the propensity score matched cohort. Children supported with centrifugal pumps had increased odds of hemolysis (odds ratio (OR) 4.03; 95% CI, 2.37–6.87), hyperbilirubinemia (OR 5.48; 95% CI, 2.62–11.49), need for inotropic support during ECMO (OR 1.54, 95% CI 1.09–2.17), metabolic alkalosis (blood pH > 7.6) during ECMO (OR 3.13; 95% CI 1.49–6.54) and acute renal failure (OR 1.61; 95% CI 1.10–2.39). Survival to hospital discharge did not differ by pump type. Conclusions: In a propensity score matched cohort of pediatric ECMO patients, children supported with centrifugal pumps had increased odds of ECMO related complications. There was no difference in survival between groups.