290 The impact of ‘the medication non-adherence’ in patients with cardiovascular disease: causes, outcomes, and interventions. Review of the literature

Abstract

Abstract Aims The adherence of the pharmacological prescriptions, for patients affected by cardiovascular chronic diseases is one of the most difficult challenges and it’s very important for the clinical efficiency of the therapy. A weak medication adherence or the non-adherence is associated with an increase in health care interventions, an increase in mortality and morbidity, and they can negatively affect the citizens and the sustainability health care system. It’s very important to pay attention to this adhesion and it is a discussed topic in the cardiovascular field. Identify the causes of medication weak adherence and/or medication non-adherence used in cardiovascular diseases and determine the resulting unfavorable clinical outcomes and possible solutions to reduce this phenomenon. Methods and results A systematic search was carried out using databases such as PUBMED and CINAHL. The inclusion criteria established, so that an article could be used, was the relevance to the topic. From the studies analyzed for the preparation of the review, it is clear that the main causes of weak adherence and/or non-adherence to drug are the long duration of the therapies, the patient’s age, and the complexity of the therapy. All this leads to unfavorable outcomes for the patient, thus determining an increase in the number of outpatient visits with the risk of hospitalization or re-hospitalization, up to an increase in mortality and/or morbidity. Conclusions The medication weak adherence or the medication non-adherence is a crucial element in the cardiovascular field that requires intervention to reduce adverse outcomes. The methods to reduce this phenomenon include health education, the interaction between patient and professionals, medical deprescribing, and the use of electronic control devices which, in recent years, have proved to be perfect allies in adherence.