290 THE ASSOCIATION BETWEEN NOCTURIA AND HYPERTENSION A LONGITUDINAL STUDY IN JAPANESE MEN AND WOMEN

Abstract

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Practice Patterns, Cost Effectiveness II1 Apr 2012290 THE ASSOCIATION BETWEEN NOCTURIA AND HYPERTENSION A LONGITUDINAL STUDY IN JAPANESE MEN AND WOMEN Yoshitaka Aoki, Yosuke Matsuta, Katsuki Tsuchiyama, Chieko Matsumoto, Yukinori Kusaka, and Osamu Yokoyama Yoshitaka AokiYoshitaka Aoki Fukui, Japan More articles by this author , Yosuke MatsutaYosuke Matsuta Fukui, Japan More articles by this author , Katsuki TsuchiyamaKatsuki Tsuchiyama Fukui, Japan More articles by this author , Chieko MatsumotoChieko Matsumoto Fukui, Japan More articles by this author , Yukinori KusakaYukinori Kusaka Fukui, Japan More articles by this author , and Osamu YokoyamaOsamu Yokoyama Fukui, Japan More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.348AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The relation between nocturia and hypertension (HT) is not clear. Some authors reported that HT was an independent risk factor for nocturia (Odds ratio 1.5-2.0), but other studies reported no association between HT and nocturia. We hypothesized that the progression or regression of noctuira may associate changes in blood pressure. To investigate the association between nocturia and hypertension, we performed a longitudinal epidemiological study. METHODS We collected data on 13,536 individuals (4,167 males and 9,369 females) who participated in a multiphasic health screening in Fukui, Japan in 2003 and 2007. We analyzed the relationships between nocturia (defined as two or more voids/night) and other variables including age, gender, body mass index (BMI, body weight in kilograms divided by the square of height in meters), high blood pressure, and impaired glucose tolerance. We defined them as follows; high BMI (≥25.0 kg/m2); high blood pressure (systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥85 mmHg); and impaired glucose tolerance (fasting glucose concentration ≥110 mg/dL). We could not include waist circumference in the definition of obesity, because waist circumference measurement was not available in our study. Chi-square tests and logistic regression models were used for statistical analysis. P-values <0.05 were considered statistically significant. RESULTS The mean age of participant was 66 years (23-95 years) in 2003. The overall prevalence of nocturia (≥2 voids/night) in 2003 and 2007 was 11.0% and 13.2%, and prevalence was higher in older age groups. In the univariate analysis, a significant relationship was found between the progression of nocturia and the following factors: age (OR 1.53), male gender (OR 1.54), and the incidence of high diastolic blood pressure (OR 1.21). A significant relationship was also found between the regression of nocturia and the following factors: age (OR 0.96), male gender (OR 0.66), the improvement of high diastolic blood pressure (OR 1.55), and impaired glucose tolerance (OR 1.21). In the multivariate analysis, a significant relationship was found between the progression of nocturia and age (OR 1.03) and male gender (1.43), and between the regression of nocturia and age (OR 0.96), male gender (0.75), the improvement of high diastolic blood pressure (OR 1.44). CONCLUSIONS The results from our epidemiological study indicate that changes of nocturia can be a marker of progression and regression for diastolic HT. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e118 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Yoshitaka Aoki Fukui, Japan More articles by this author Yosuke Matsuta Fukui, Japan More articles by this author Katsuki Tsuchiyama Fukui, Japan More articles by this author Chieko Matsumoto Fukui, Japan More articles by this author Yukinori Kusaka Fukui, Japan More articles by this author Osamu Yokoyama Fukui, Japan More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...