Abstract

Brain natriuretic peptide (BNP) is expected to be related to left atrial pressure, which can also be estimated using tissue Doppler echocardiography. Aims: To assess the relationship between BNP level and measures el systolic and diastolic function on Tissue Doppler Imaging (Tdi) in patients with aortic stenosis. Methods: We studied 50 patients with asymptomalic moderate to severe aortic slenosis (EOA 100pgml) gave an AUC of 08 for the septal systolic velocity and 0.7 lor the E/E' ratio. An E,,E' ratio > 10 gave a sensitivity of 76% and specificity 30% for a high BNP while a ratio > 15 gave a sensitivity 67% and specificity 87%. A systolic velocily 15 reliably predict a high BNP level.

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