Abstract

Ecthyma is an ulcerative pyoderma of the skin, well known to be caused by S aureus and/or group A Streptococcus. Bevacizumab is an IgG1 humanized monoclonal antibody that neutralizes the effect of vascular endothelial growth factor (VEGF), which is for use in the treatment of multiple cancer. However, in bevacizumab, by inhibiting the pathway of VEGF that can interfere wound repair, and several cases have been reported of delayed wound healing in postoperative patients with bevacizumab. In our case, it is highly possible that bevacizumab disrupted wound healing process, and that ecthyma was caused by a secondary infection at the injection site.

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