Abstract
Background: Among women, breast cancer (BC) is the most frequently diagnosed cancer and is ranked as the leading cause of cancer death. Given that aging is one of the strongest risk factors for the development of breast cancer, older adults (65+) are disproportionately affected. At the same time, more than half of older cancer patients are considered frail or pre-frail and are at increased risk of adverse outcomes including treatment intolerance, as well as morbidity, and mortality. Frailty is thus recognized as an important metric to guide decision-making in geriatric oncology.
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