Abstract

AbstractRecent infectious disease outbreaks have stimulated multiple institutional and operational efforts by governments, international organizations, and the private sector to ensure the world is better prepared to respond to epidemics. One of the critical advances has been the greater engagement of international financial institutions (IFIs) in supporting preparedness for and response to emerging and re-emerging infectious diseases (EIDs) with epidemic potential. Despite progress on preparedness and response, including the launch of initiatives such as the Coalition for Epidemic Preparedness Initiatives (CEPI), the world is not well prepared for the next pandemic, and research and development (R&D) for medical countermeasures against EIDs requires more attention, coordination, and investment. IFI investments in health security have so far focused primarily on disease surveillance, laboratory capacity, outbreak readiness, and human resources for health security, under initiatives that have not so far included sufficient focus on R&D for preparedness and accelerated development of new vaccines, therapeutics, and diagnostics (VTD) against novel pathogens.This chapter examines how IFIs can better contribute to the advancement of EID preparedness and response. It describes IFI initiatives, including those by the World Bank, that complement other global efforts to galvanize emergency research during EID outbreaks. IFI initiatives seek to strengthen national and regional infectious disease response systems. Through IFI financial management expertise, leveraging IFIs’ comparative advantage in fund management services and their use of development lending, IFIs also seek to bolster core capacity at the intersection of health systems and clinical research. This chapter also notes some constraints faced by IFIs in financing clinical research and examines lessons and opportunities for IFIs to accelerate investment in emergency research.

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