Abstract
Previous research has shown that marketed mild amino-acid surfactant based bodywashes and isethionate syndet bars containing free fatty acids can not only deposit but also deliver the fatty acids deeper into the viable epidermis, which are subsequently elongated into longer chain fatty acids. Further details on ceramide formation and metabolism dynamics are of interest to understand the fate of the delivered fatty acids. The objective of this research was to determine if the fatty acids deposited by cleansers are incorporated into skin ceramides and investigate the duration of the conversion.
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