275 Penile Pain Profiles in Patients with Peyronies Disease (PD)

Abstract

Little analysis has been conducted of penile pain in men with PD despite its association with patient bother. To analyze penile pain profiles in our PD population. As part of our initial patient evaluation, men are given a set of questions assessing penile pain including: presence in flaccid and erect state as well as intensity (measured using a 0-10 scale). Correlates of pain were sought including patient age, PD duration, erectile function, location of plaque. Statistical analysis was performed using t-test for continuous variables and chi-square test for categorical variables. Medical records of 306 patients were analyzed. 112 (37%) patients reported penile pain. 60% of pain sufferers had pain in the erect state only, 23% had both erect and flaccid pain, 9% had flaccid pain only and 8% did not answered. For men reporting erect pain, mean pain was 4.94 (SD = 2.27), similarly for men reporting flaccid pain, mean pain was 3.68 (SD = 2.09); this difference was statistically significant (p=0.044). PD duration was significantly shorter (p = 0.036) in the group with any pain (mean 12.98, SD = 19.81 months) versus those with none (mean 21.70, SD = 39.27). From patients with erect penile pain, 36% had PD duration of <6m, 21% had PD for 6-12m and 44% had for longer than 12m. From patients with flaccid pain, 33% had PD duration of <6m, 20% had PD for 6-12m and 47% had for longer than 12m (p=0.528 for comparison to men with erect pain). Penile pain did not impact patient ability to penetrate in this analyzes, probably due to PP relatively low mean PP intensity in VAS.