Abstract
Background: Axillary lymph node staging is a determining factor in the treatment and prognosis of patients with breast cancer. One-step nucleic acid amplification (OSNA) is a molecular procedure that allows assessment of the total tumor load (TTL) in axillary sentinel lymph node (ASLN) and can be used to predict extra lymph node metastasis in early breast cancer. The primary location of the breast tumor seems to be closely related to ASLN positivity. The purpose of this study was to determine whether the primary location of the tumor could have an influence on TTL.
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