Abstract
Collagen is the main component of the skin extracellular matrix and plays an integral role in supporting and maintaining the structure and biomechanical properties of the skin. There is increased interest to understand how collagen quality is controlled by the skin’s fibroblast cells, particularly in aging, and to quantify how product formulations improve the appearance of aging skin. In this work, we have developed a new in vitro tool to visualize collagen in skin fibroblasts at high speed and high resolution using live cell imaging and super resolution microscopy.
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